Chang Gon Kim, Min Hee Hong*, Dahee Kim*, Brian Hyohyoung Lee*, Hyunwook Kim*, Chan-Young Ock*, Geoffrey Kelly, Yoon Ji Bang, Gamin Kim, Jung Eun Lee, Chaeyeon Kim, Se-Heon Kim, Hyun Jun Hong, Young Min Park, Nam Suk Sim, Heejung Park, Jin Woo Park, Chang Geol Lee, Kyung Hwan Kim, Goeun Park, Inkyung Jung, Dawoon Han, Jong Hoon Kim, Junha Cha, Insuk Lee, Mingu Kang, Heon Song, Chiyoon Oum, Seulki Kim, Sukjun Kim, Yoojoo Lim, Seunghee Kim-Schulze, Miriam Merad, Sun Och Yoon, Hyun Je Kim, Yoon Woo Koh, Hye Ryun Kim. A phase II open-label randomized clinical trial of preoperative durvalumab or durvalumab plus tremelimumab in resectable head and neck squamous cell carcinoma. Clinical Cancer Research. 2024 Mar 8. doi: 10.1158/1078-0432.CCR-23-3249. Epub ahead of print. PMID: 38457288.

Brian Hyohyoung Lee, Yoon Ji Bang*, Sung Ha Lim*, Seong-Jun Kang, Sung Hee Kim, Seunghee Kim-Schulze, Chung-Gyu Park, Hyun Je Kim, Tae-Gyun Kim. High-dimensional profiling of regulatory T cells in psoriasis reveals an impaired skin-trafficking property. eBioMedicine. 2024 Feb;1 00:104985. doi: 10.1016/j.ebiom.2024.104985. Epub 2024 Feb 1. PMID: 38306895; PMCID: PMC10847473.

Christine Suh-Yun Joh, Soyoung Jeong*, Cheol Lee*, Hee Jung Lee, Jung Ho Lee, Hyun Seung Choi, Soyun Cho, Gwangil Kim, Jaehwan Kim, James G Krueger, Chung-Gyu Park, Seon-Pil Jin, Hyun Je Kim, Jung U Shin. Spatial transcriptomic profiling reveals the pathophysiology of early-stage hidradenitis suppurativa. Br J Dermatol. 2023 Aug 17:ljad274. doi: 10.1093/bjd/ljad274. PMID: 37590958.

Jung Ho Lee, Brian H Lee, Soyoung Jeong, Christine Suh-Yun Joh, Hyo Jeong Nam, Hyun Seung Choi, Henry Sserwadda, Ji Won Oh, Chung-Gyu Park, Seon-Pil Jin, Hyun Je Kim. Single-cell RNA sequencing identifies distinct transcriptomic signatures between PMA/ionomycin- and αCD3/αCD28-activated primary human T cells. Genomics Inform. 2023 Jun;21(2):e18. doi: 10.5808/gi.23009. Epub 2023 Jun 30. PMID: 37704208; PMCID: PMC10326540.

Sunho Lee, Sunyoung Jung*, Hyun Je Kim*, Sueon Kim, Ji Hwan Moon, Hyunwoo Chung, Seong-Jun Kang, Chung-Gyu Park. Mesenchymal stem cell-derived extracellular vesicles subvert the Th17 cell by destabilizing RORγt through post-translational modification. Experimental & Molecular Medicine 2023 Apr;55(4):870. doi: 10.1038/s12276-023-01001-4. Erratum for: Exp Mol Med. 2023 Mar;55(3):665-679. PMID: 37100897; PMCID: PMC10167263.

Lim Y, Kang SJ, Cho BK, Kim HJ, Mun JH, Roh MR, Gulati N, Yang HJ, Moon JH, Won CH, Park CG. Intra-tumoral heterogeneity and immune escape of melanoma arising from congenital melanocytic nevus revealed by spatial gene expression profiling. J Eur Acad Dermatol Venereol. 2022 Dec;36(12):e1044-e1047. doi: 10.1111/jdv.18443.

Joo EH, Bae JH, Park JH, Bang YJ, Han J, Gulati N, Kim JI, Park CG, Park WY and Kim HJ. Deconvolution of Adult T-Cell Leukemia/Lymphoma With Single-CellRNA-Seq Using Frozen Archived Skin Tissue Reveals New Subset of Cancer Associated Fibroblast. Front. Immunol. 2022; 13:856363. doi: 10.3389/fimmu.2022.856363.

Dong-Min Kim, Yuri Kim, Jun-Won Seo, Jooyeon Lee, Uni Park, Na-Young Ha, Jaemoon Koh, Hyoree Park, Jae-Won Lee, Hyo-Jin Ro, Na Ra Yun, Da Young Kim, Sung Ho Yoon, Yong Sub Na, Do Sik Moon, Sung-Chul Lim, Choon-Mee Kim, Kyeongseok Jeon, Jun-Gu Kang, Na-Yoon Jang, Hyeongseok Jeong, Jungok Kim, Shinhyea Cheon, Kyung Mok Sohn, Jae Youg Moon, Sungmin Kym, Seung Ro Han, Myung-Shin Lee, Hyun-Je Kim, Woong-Yang Park, Ji-Yeob Choi, Hyun-Woo Shin, Hye-Young Kim, Chung-Hyun Cho, Yoon Kyung Jeon, Yeon-Sook Kim, Nam-Hyuk Cho. Enhanced eosinophil-mediated inflammation associated with antibody and complement-dependent pneumonic insults in critical COVID-19. Cell Rep 2021 Oct 5;37(1):109798. doi: 10.1016/j.celrep.2021.109798. Epub 2021 Sep 20.

Kim HJ, Shim JH, Park JH, Shin HT, Shim JS, Jang KT, Park WY, Lee KH, Kwon EJ, Jang HS, Yang H, Lee JH, Yang JM, Lee D. Single-cell RNA sequencing of human nail unit defines RSPO4 onychofibroblasts and SPINK6 nail epithelium. Commun Biol. 2021 Jun 7;4(1):692. doi: 10.1038/s42003-021-02223-w.

Kim JM, Hong SH, Shin JS, Min BH, Kim HJ, Chung H, Kim J, Bang YJ, Seo S, Hwang ES, Kang HJ, Ha J, Park CG. Long-term control of diabetes in a nonhuman primate by two separate transplantations of porcine adult islets under immunosuppression. Am J Transplant. 2021 May 31. doi: 10.1111/ajt.16704.

Kim J, Lee J, Kim HJ, Kameyama N, Nazarian R, Der E, Cohen S, Guttman-Yassky E, Putterman C, Krueger JG. Single-cell transcriptomics applied to emigrating cells from psoriasis elucidate pathogenic versus regulatory immune cell subsets. J Allergy Clin Immunol. 2021 Apr 29:S0091-6749(21)00662-X.

Park JH, Yoon D, Lee J, Oh SJ, Kim HJ, Lee JH, Lee DY. Clinical profile of cutaneous adverse events of immune checkpoint inhibitors in a single tertiary center. J Dermatol. 2021 Jul;48(7):979-988.

Czarnowicki T, Kim HJ**, Villani AP, Glickman J, Duca ED, Han J, Pavel AB, Lee BH, Rahman AH, Merad M, Krueger JG, Guttman-Yassky E. High-dimensional analysis defines multicytokine T-cell subsets and supports a role for IL-21 in atopic dermatitis. Allergy. 2021 Apr 5. 

Hong SH, Kim HJ, Kang SJ, Park CG. Novel Immunomodulatory Approaches for Porcine Islet Xenotransplantation. Curr Diab Rep. 2021 Jan 12;21(1):3.

Park JH, Choi Y, Kim HJ, Oh SJ, Lee DY, Lee JH, Lee JH. Duration of Oral Antibiotics Administration for Cetuximab-Induced Acneiform Eruption. Dermatology. 2021;237(3):457-463.

Kim JM, Hong SH, Chung H, Shin JS, Min BH, Kim HJ, Kim J, Hwang ES, Kang HJ, Ha J, Park CG. Long-term porcine islet graft survival in diabetic non-human primates treated with clinically available immunosuppressants. Xenotransplantation. 2021 Mar;28(2):e12659

He H, Del Duca E, Diaz A, Kim HJ, Gay-Mimbrera J, Zhang N, Wu J, Beaziz J, Estrada Y, Krueger JG, Pavel AB, Ruano J, Guttman-Yassky E. Mild atopic dermatitis lacks systemic inflammation and shows reduced nonlesional skin abnormalities. J Allergy Clin Immunol. 2021 Apr;147(4):1369-1380.

Park JH, Byun HJ, Kim HJ, Oh SJ, Choi C, Noh JM, Oh D, Lee JH, Lee DY. Effect of photobiomodulation therapy on radiodermatitis in a mouse model: an experimental animal study. Lasers Med Sci. 2021 Jun;36(4):843-853.

Chang SH, Kim HJ, Park CG. Allogeneic ADSCs Induce the Production of Alloreactive Memory-CD8 T Cells through HLA-ABC Antigens. Cells. 2020 May 18;9(5):1246.

Lee SJ, Kim HJ*, Byun NR, Park CG. Donor-Specific Regulatory T Cell-Mediated Immune Tolerance in an Intrahepatic Murine Allogeneic Islet Transplantation Model with Short-Term Anti-CD154 mAb Single Treatment. Cell Transplant. 2020 Jan-Dec;29:963689720913876.

He H, Suryawanshi H, Morozov P, Gay-Mimbrera J, Del Duca E, Kim HJ, Kameyama N, Estrada Y, Der E, Krueger JG, Ruano J, Tuschl T, Guttman-Yassky E. Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis. J Allergy Clin Immunol. 2020 Jun;145(6):1615-1628. (First scRNAseq paper with Human AD skin tissue: 

Kim HJ**, Moon JH, Chung H, Shin JS, Kim B, Kim JM, Kim JS, Yoon IH, Min BH, Kang SJ, Kim YH, Jo K, Choi J, Chae H, Lee WW, Kim S, Park CG. Bioinformatic analysis of peripheral blood RNA-sequencing sensitively detects the cause of late graft loss following overt hyperglycemia in pig-to-nonhuman primate islet xenotransplantation. Sci Rep. 2019 Dec 11;9(1):18835.

Chung H, Kim HJ**, Kim JS, Yoon IH, Min BH, Shin JS, Kim JM, Lee WW, Park CG. CD4+ /CD8+ T-cell ratio correlates with the graft fate in pig-to-non-human primate islet xenotransplantation. Xenotransplantation. 2020 Mar;27(2):e12562.

Czarnowicki T, He H, Canter T, Han J, Lefferdink R, Erickson T, Rangel S, Kameyama N, Kim HJ, Pavel AB, Estrada Y, Krueger JG, Paller AS, Guttman-Yassky E. Evolution of pathologic T-cell subsets in patients with atopic dermatitis from infancy to adulthood. J Allergy Clin Immunol. 2020 Jan;145(1):215-228.

Pavel AB, Song T, Kim HJ, Del Duca E, Krueger JG, Dubin C, Peng X, Xu H, Zhang N, Estrada YD, Denis L, Rao N, Gupta S, Zammit DJ, Bissonnette R, Guttman-Yassky E., Oral Janus kinase/SYK inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in patients with atopic dermatitis. J Allergy Clin Immunol. 2019 Oct;144(4):1011-1024.

Yoon IH, Chung H, Kim HJ**, Nam HY, Shin JS, Kim YH, Park CG. Peri-graft porcine-specific CD4+ FoxP3+ regulatory T cells by CD40-CD154 blockade prevented the rejection of porcine islet graft in diabetic mice. Xenotransplantation. 2019 Sep;26(5):e12533.

Chung H, Hong SJ, Choi SW, Koo JY, Kim M, Kim HJ, Park SB, Park CG. High mobility group box 1 secretion blockade results in the reduction of early pancreatic islet graft loss. Biochem Biophys Res Commun. 2019 Jul 5;514(4):1081-1086.

Czarnowicki T, He H, Leonard A, Kim HJ, Kameyama N, Pavel AB, Li R, Estrada Y, Wen HC, Kimmel GW, Kim HJ, Chima M, Lebwohl M, Krueger JG, Guttman-Yassky E. Blood endotyping distinguishes the profile of vitiligo from that of other inflammatory and autoimmune skin diseases. J Allergy Clin Immunol. 2019 Jun;143(6):2095-2107.

Brunner PM, Israel A, Leonard A, Pavel AB, Kim HJ, Zhang N, Czarnowicki T, Patel K, Murphrey M, Ramsey K, Rangel S, Zebda R, Soundararajan V, Zheng X, Estrada YD, Xu H, Krueger JG, Paller AS, Guttman-Yassky E. Distinct transcriptomic profiles of early-onset atopic dermatitis in blood and skin of pediatric patients. Ann Allergy Asthma Immunol. 2019 Mar;122(3):318-330.e3.

Min BH, Shin JS, Kim JM, Kang SJ, Kim HJ, Yoon IH, Park SK, Choi JW, Lee MS, Park CG. Delayed revascularization of islets after transplantation by IL-6 blockade in pig to non-human primate islet xenotransplantation model. Xenotransplantation. 2018 Jan;25(1):10.1111/xen.12374.

Shin JS, Kim JM, Min BH, Yoon IH, Kim HJ, Kim JS, Kim YH, Kang SJ, Kang HJ, Lim DG, Ha JW, Kim SJ, Park WB, Park CG. Pre-clinical results in pig-to-nonhuman primate islet xenotransplantation using anti-CD40 antibody (2C10R4) - based immunosuppression. Xenotransplantation. 2018 Jan;25(1).

Yu SJ, Kim HJ**, Lee ES, Park CG, Cho SJ, Jeon SH. β-Catenin Accumulation is Associated with Increased Expression of Nanog Protein and Predicts Maintenance of MSC Self-renewal. Cell Transplant. 2017 Feb;26(2):365-377

Kim HJ**, Byun N, Kwon O, Park CG. Cross-sensitization between xeno- and allo-antigens on subsequent allogeneic and xenogeneic pancreatic islet transplantation in a murine model. Biochem Biophys Res Commun. 2016 Nov;480(3):474-478

Kim JM, Shin JS, Min BH, Kim HJ, Kim JS, Yoon IH, Jeong WY, Lee GE, Kim MS, Kim JE, Jin SM, Park CG. Induction, management, and complications of streptozotocin-induced diabetes mellitus in rhesus monkeys. Xenotransplantation. 2016 Nov;23(6):472-478.

Kim JM, Kim HJ**, Min BH, Shin JS, Jeong WY, Lee GE, Kim MS, Kim JE, Park CG. Bullous pemphigoid-like skin blistering disease in a rhesus macaque (Macaca mulatta). J Med Primatol. 2016 Aug;45(4):206-8.

Kim HJ**, Yoon IH, Min BH, Kim YH, Shin JS, Kim JM, Kim JS, Nam HY, Lee WW, Park CG. Porcine antigen-specific IFN-γ ELISpot as a potentially valuable tool for monitoring cellular immune responses in pig-to-non-human primate islet xenotransplantation. Xenotransplantation. 2016 Jul;23(4):310-9

Shin JS, Min BH, Kim JM, Kim JS, Yoon IH, Kim HJ, Kim YH, Jang JY, Kang HJ, Lim DG, Ha J, Kim SJ, Park CG. Failure of transplantation tolerance induction by autologous regulatory T cells in the pig-to-non-human primate islet xenotransplantation model. Xenotransplantation. 2016 Jul;23(4):300-9.

Kim JS, Byun N, Chung H, Kim HJ, Kim JM, Chun T, Lee WW, Park CG. Cell enrichment-free massive ex-vivo expansion of peripheral CD20⁺ B cells via CD40-CD40L signals in non-human primates. Biochem Biophys Res Commun. 2016 Apr;473(1):92-8

Byun N, Kim HJ**, Min BH, Shin JS, Yoon IH, Kim JM, Kim YH, Park CG. A novel method for murine intrahepatic islet transplantation via cecal vein. J Immunol Methods. 2015 Dec; 427:122-125.

Shin JS, Kim JM, Kim JS, Min BH, Kim YH, Kim HJ, Jang JY, Yoon IH, Kang HJ, Kim J, Hwang ES, Lim DG, Lee WW, Ha J, Jung KC, Park SH, Kim SJ, Park CG. Long-term control of diabetes in immunosuppressed nonhuman primates (NHP) by the transplantation of adult porcine islets. Am J Transplant. 2015 Nov;15(11):2837-50.